14 kDa phosphohistidine phosphatase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9NRX4. Use UniProt Q9NRX4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NRX4 as the stable identity anchor, then attach disease evidence before program review.
14 kDa phosphohistidine phosphatase
Review this target as 14 kDa phosphohistidine phosphatase, mapped to UniProt Q9NRX4. Sequence length is 125 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 14 kDa phosphohistidine phosphatase as ChEMBL target CHEMBL5169200, mapped to UniProt Q9NRX4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 14 kDa phosphohistidine phosphatase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9NRX4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 14 kDa phosphohistidine phosphatase |
| UniProt Accession | Q9NRX4 |
| Component Type | Protein |
| Sequence Length | 125 aa |
14 kDa phosphohistidine phosphatase
Review this target as 14 kDa phosphohistidine phosphatase, mapped to UniProt Q9NRX4. Sequence length is 125 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5653589 | 7.24 | Kd | 57.79 | Preclinical |
| CHEMBL228281 | 5.1 | IC50 | 7900.0 | Preclinical |
| CHEMBL456 | 4.74 | IC50 | 18300.0 | Approved |
| CHEMBL173530 | 4.66 | IC50 | 22000.0 | Preclinical |
| CHEMBL1321154 | 4.1 | IC50 | 80000.0 | Preclinical |
| CHEMBL228281 | 4.05 | Ki | 90000.0 | Preclinical |
| CHEMBL1330792 | 4.0 | IC50 | 100000.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 12 | 5 | 4.9 |
| assay format | 8 | 2 | 4.7 |