Use UniProt D5JEH1 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5169215 Target Snapshot
Venus kinase receptor 2 · SINGLE PROTEIN · Schistosoma mansoni
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As of 2026-09-14Protein identity stays anchored to UniProt D5JEH1. Use UniProt D5JEH1 as the stable identity anchor, then attach disease evidence before program review.
Venus kinase receptor 2
Review this target as Venus kinase receptor 2, mapped to UniProt D5JEH1. Sequence length is 1641 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Venus kinase receptor 2 as ChEMBL target CHEMBL5169215, mapped to UniProt D5JEH1. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Venus kinase receptor 2 is the right protein anchor across sources, using UniProt D5JEH1 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Venus kinase receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Schistosoma mansoni |
| UniProt | D5JEH1 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Venus kinase receptor 2 |
| UniProt Accession | D5JEH1 |
| Component Type | Protein |
| Sequence Length | 1641 aa |
Venus kinase receptor 2
How to read this target
Review this target as Venus kinase receptor 2, mapped to UniProt D5JEH1. Sequence length is 1641 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL587965 | 6.36 | Kd | 440.0 | Preclinical |
| CHEMBL1835064 | 5.71 | Kd | 1960.0 | Preclinical |
| CHEMBL473080 | 5.6 | Kd | 2530.0 | Preclinical |
| CHEMBL496162 | 5.47 | Kd | 3400.0 | Preclinical |
| CHEMBL515757 | 5.35 | Kd | 4500.0 | Preclinical |
| CHEMBL1835064 | 5.25 | IC50 | 5690.0 | Preclinical |
| CHEMBL587965 | 5.19 | IC50 | 6470.0 | Preclinical |
| CHEMBL453707 | 5.11 | Kd | 7800.0 | Preclinical |
| CHEMBL520954 | 5.09 | Kd | 8200.0 | Preclinical |
| CHEMBL257167 | 4.8 | Kd | 16000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 12 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 12 | 5.1 |