BCL2/BID · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P10415. Use UniProt P10415 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10415 as the stable identity anchor, then attach disease evidence before program review.
Apoptosis regulator Bcl-2
Review this target as BCL2/BID, mapped to UniProt P10415. ChEMBL maps the protein component as Apoptosis regulator Bcl-2. Sequence length is 239 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats BCL2/BID as ChEMBL target CHEMBL5169265, mapped to UniProt P10415. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | BCL2/BID |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | P10415 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Apoptosis regulator Bcl-2 |
| UniProt Accession | P10415 |
| Component Type | Protein |
| Sequence Length | 239 aa |
Apoptosis regulator Bcl-2
Review this target as BCL2/BID, mapped to UniProt P10415. ChEMBL maps the protein component as Apoptosis regulator Bcl-2. Sequence length is 239 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4848284 | 6.51 | Ki | 310.0 | Preclinical |
| CHEMBL297453 | 6.35 | IC50 | 450.0 | Clinical |
| CHEMBL5204188 | 6.27 | Ki | 540.0 | Preclinical |
| CHEMBL5199461 | 6.23 | Ki | 590.0 | Preclinical |
| CHEMBL5203252 | 6.09 | Ki | 810.0 | Preclinical |
| CHEMBL5183108 | 6.03 | Ki | 940.0 | Preclinical |
| CHEMBL5206049 | 6.0 | Ki | 1000.0 | Preclinical |
| CHEMBL5181865 | 5.96 | Ki | 1100.0 | Preclinical |
| CHEMBL5090868 | 5.92 | Ki | 1200.0 | Preclinical |
| CHEMBL5196159 | 5.72 | Ki | 1900.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 7 | 18 | 5.7 |