Sodium- and chloride-dependent GABA transporter 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P48066. Use UniProt P48066 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P48066 as the stable identity anchor, then attach disease evidence before program review.
Sodium- and chloride-dependent GABA transporter 3
Review this target as Sodium- and chloride-dependent GABA transporter 3, mapped to UniProt P48066. Sequence length is 632 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium- and chloride-dependent GABA transporter 3 as ChEMBL target CHEMBL5208, mapped to UniProt P48066. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium- and chloride-dependent GABA transporter 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P48066 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium- and chloride-dependent GABA transporter 3 |
| UniProt Accession | P48066 |
| Component Type | Protein |
| Sequence Length | 632 aa |
Sodium- and chloride-dependent GABA transporter 3
Review this target as Sodium- and chloride-dependent GABA transporter 3, mapped to UniProt P48066. Sequence length is 632 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL96 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL75035 | 5.95 | IC50 | 1120.0 | Preclinical |
| CHEMBL2403781 | 5.8 | IC50 | 1590.0 | Preclinical |
| CHEMBL4458674 | 5.72 | IC50 | 1900.0 | Preclinical |
| CHEMBL1788265 | 5.64 | IC50 | 2300.0 | Preclinical |
| CHEMBL349005 | 5.6 | IC50 | 2511.89 | Preclinical |
| CHEMBL4447559 | 5.56 | IC50 | 2754.23 | Preclinical |
| CHEMBL4845832 | 5.53 | IC50 | 2950.0 | Preclinical |
| CHEMBL4126078 | 5.5 | IC50 | 3160.0 | Preclinical |
| CHEMBL432737 | 5.3 | IC50 | 5000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 21 | 25 | 5.2 |
| single protein format | 6 | 26 | 4.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 5 | — |