Cyclin-dependent kinase 1 · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-13Protein identity stays anchored to UniProt P00546. Use UniProt P00546 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00546 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 1
Review this target as Cyclin-dependent kinase 1, mapped to UniProt P00546. Sequence length is 298 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclin-dependent kinase 1 as ChEMBL target CHEMBL5213, mapped to UniProt P00546. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cyclin-dependent kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P00546 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 1 |
| UniProt Accession | P00546 |
| Component Type | Protein |
| Sequence Length | 298 aa |
Cyclin-dependent kinase 1
Review this target as Cyclin-dependent kinase 1, mapped to UniProt P00546. Sequence length is 298 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL23327 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL23254 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL75680 | 5.6 | IC50 | 2500.0 | Preclinical |
| CHEMBL311228 | 5.16 | IC50 | 7000.0 | Preclinical |
| CHEMBL70590 | 4.62 | IC50 | 24000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 5 | 5.7 |