Integrin-linked protein kinase · SINGLE PROTEIN · Homo sapiens
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt Q13418. Use UniProt Q13418 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13418 as the stable identity anchor, then attach disease evidence before program review.
Scaffold protein ILK
Review this target as Integrin-linked protein kinase, mapped to UniProt Q13418. ChEMBL maps the protein component as Scaffold protein ILK. Sequence length is 452 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Integrin-linked protein kinase as ChEMBL target CHEMBL5247, mapped to UniProt Q13418. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Integrin-linked protein kinase is the right protein anchor across sources, using UniProt Q13418 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Integrin-linked protein kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13418 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Scaffold protein ILK |
| UniProt Accession | Q13418 |
| Component Type | Protein |
| Sequence Length | 452 aa |
Scaffold protein ILK
Review this target as Integrin-linked protein kinase, mapped to UniProt Q13418. ChEMBL maps the protein component as Scaffold protein ILK. Sequence length is 452 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3681007 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL3681013 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL3685712 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL3639798 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL3685682 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL3685727 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL255863 | 7.7 | Kd | 20.0 | Approved |
| CHEMBL3732995 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL2079588 | 7.5 | Kd | 32.0 | Clinical |
| CHEMBL3680995 | 7.4 | IC50 | 40.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 34 | 155 | 6.3 |
| subcellular format | 20 | 3 | 7.0 |
| single protein format | 16 | 16 | 5.3 |
| assay format | 1 | 151 | 6.3 |