Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL5269 Target Snapshot

Solute carrier family 22 member 20 · SINGLE PROTEIN · Mus musculus

45Compounds
2Assays
5Approved Drugs
80.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q80UJ1. Use UniProt Q80UJ1 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q80UJ1 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Solute carrier family 22 member 20 as ChEMBL target CHEMBL5269, mapped to UniProt Q80UJ1. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Solute carrier family 22 member 20
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL5269
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q80UJ1
Solute carrier family 22 member 20
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Solute carrier family 22 member 20 is the right protein anchor across sources, using UniProt Q80UJ1 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSolute carrier family 22 member 20
UniProt AccessionQ80UJ1
Component TypeProtein
Sequence Length556 aa

Solute carrier family 22 member 20

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Solute carrier family 22 member 20, mapped to UniProt Q80UJ1. Sequence length is 556 aa.

Mapped IDQ80UJ1
Review nameSolute carrier family 22 member 20
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

5
Approved
1
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

KI80.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL521 5.96 Ki 1100.0 Approved
CHEMBL376503 5.36 Ki 4365.16 Preclinical
CHEMBL1162485 5.18 Ki 6600.0 Preclinical
CHEMBL1162486 5.18 Ki 6606.93 Preclinical
CHEMBL1162487 5.18 Ki 6606.93 Preclinical
CHEMBL320358 5.09 Ki 8128.31 Preclinical
CHEMBL897 5.08 Ki 8400.0 Approved
CHEMBL14184 5.05 Ki 9000.0 Preclinical
CHEMBL541 4.86 Ki 13800.0 Preclinical
CHEMBL548 4.75 Ki 18000.0 Approved
Distribution

pChEMBL Value Distribution

12
5.0
2
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

2
Total Assays
44
Tested Compounds
1
Assay Types
Binding — 2 assays, 44 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 44 4.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine