3-dehydroquinate dehydratase · SINGLE PROTEIN · Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
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As of 2026-09-13Protein identity stays anchored to UniProt P15474. Use UniProt P15474 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15474 as the stable identity anchor, then attach disease evidence before program review.
3-dehydroquinate dehydratase
Review this target as 3-dehydroquinate dehydratase, mapped to UniProt P15474. Sequence length is 157 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 3-dehydroquinate dehydratase as ChEMBL target CHEMBL5276, mapped to UniProt P15474. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 3-dehydroquinate dehydratase |
| Target Type | SINGLE PROTEIN |
| Organism | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
| UniProt | P15474 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 3-dehydroquinate dehydratase |
| UniProt Accession | P15474 |
| Component Type | Protein |
| Sequence Length | 157 aa |
3-dehydroquinate dehydratase
Review this target as 3-dehydroquinate dehydratase, mapped to UniProt P15474. Sequence length is 157 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1823559 | 8.24 | Ki | 5.7 | Preclinical |
| CHEMBL3221803 | 8.24 | Ki | 5.7 | Preclinical |
| CHEMBL3221799 | 7.54 | Ki | 29.0 | Preclinical |
| CHEMBL3221802 | 7.32 | Ki | 48.0 | Preclinical |
| CHEMBL3221805 | 7.14 | Ki | 73.0 | Preclinical |
| CHEMBL3221800 | 7.11 | Ki | 78.0 | Preclinical |
| CHEMBL3221804 | 6.66 | Ki | 217.0 | Preclinical |
| CHEMBL3221801 | 5.76 | Ki | 1720.0 | Preclinical |
| CHEMBL1261 | 5.14 | Kd | 7300.0 | Approved |
| CHEMBL345567 | 5.1 | Ki | 8000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 20 | 4.5 |
| cell-based format | 1 | 8 | 7.2 |