Alpha-ketoglutarate-dependent dioxygenase AlkB · SINGLE PROTEIN · Escherichia coli (strain K12)
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As of 2026-09-14Protein identity stays anchored to UniProt P05050. Use UniProt P05050 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P05050 as the stable identity anchor, then attach disease evidence before program review.
Alpha-ketoglutarate-dependent dioxygenase AlkB
Review this target as Alpha-ketoglutarate-dependent dioxygenase AlkB, mapped to UniProt P05050. Sequence length is 216 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alpha-ketoglutarate-dependent dioxygenase AlkB as ChEMBL target CHEMBL5291506, mapped to UniProt P05050. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Alpha-ketoglutarate-dependent dioxygenase AlkB |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli (strain K12) |
| UniProt | P05050 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alpha-ketoglutarate-dependent dioxygenase AlkB |
| UniProt Accession | P05050 |
| Component Type | Protein |
| Sequence Length | 216 aa |
Alpha-ketoglutarate-dependent dioxygenase AlkB
Review this target as Alpha-ketoglutarate-dependent dioxygenase AlkB, mapped to UniProt P05050. Sequence length is 216 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1230640 | 4.99 | IC50 | 10200.0 | Preclinical |
| CHEMBL418068 | 4.9 | IC50 | 12700.0 | Preclinical |
| CHEMBL5286796 | 4.71 | IC50 | 19370.0 | Preclinical |
| CHEMBL5173876 | 4.47 | IC50 | 33500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 6 | 4.8 |