Use UniProt Q80W65 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5291514 Target Snapshot
Proprotein convertase subtilisin/kexin type 9 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q80W65. Use UniProt Q80W65 as the stable identity anchor, then attach disease evidence before program review.
Proprotein convertase subtilisin/kexin type 9
Review this target as Proprotein convertase subtilisin/kexin type 9, mapped to UniProt Q80W65. Sequence length is 694 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Proprotein convertase subtilisin/kexin type 9 as ChEMBL target CHEMBL5291514, mapped to UniProt Q80W65. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Proprotein convertase subtilisin/kexin type 9 is the right protein anchor across sources, using UniProt Q80W65 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Proprotein convertase subtilisin/kexin type 9 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q80W65 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proprotein convertase subtilisin/kexin type 9 |
| UniProt Accession | Q80W65 |
| Component Type | Protein |
| Sequence Length | 694 aa |
Proprotein convertase subtilisin/kexin type 9
How to read this target
Review this target as Proprotein convertase subtilisin/kexin type 9, mapped to UniProt Q80W65. Sequence length is 694 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5271747 | 9.0 | Kd | 1.0 | Preclinical |
| CHEMBL5278292 | 7.68 | Kd | 21.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 2 | 8.3 |