Plasma membrane ATPase 1 · SINGLE PROTEIN · Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P05030. Use UniProt P05030 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P05030 as the stable identity anchor, then attach disease evidence before program review.
Plasma membrane ATPase 1
Review this target as Plasma membrane ATPase 1, mapped to UniProt P05030. Sequence length is 918 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Plasma membrane ATPase 1 as ChEMBL target CHEMBL5291521, mapped to UniProt P05030. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Plasma membrane ATPase 1 is the right protein anchor across sources, using UniProt P05030 as the stable mapping.
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| Preferred Name | Plasma membrane ATPase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| UniProt | P05030 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Plasma membrane ATPase 1 |
| UniProt Accession | P05030 |
| Component Type | Protein |
| Sequence Length | 918 aa |
Plasma membrane ATPase 1
Review this target as Plasma membrane ATPase 1, mapped to UniProt P05030. Sequence length is 918 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3359320 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL5270653 | 5.26 | IC50 | 5500.0 | Preclinical |
| CHEMBL4548520 | 5.16 | IC50 | 6900.0 | Preclinical |
| CHEMBL4289313 | 5.13 | IC50 | 7400.0 | Preclinical |
| CHEMBL5273581 | 5.01 | IC50 | 9700.0 | Preclinical |
| CHEMBL5267780 | 4.96 | IC50 | 11100.0 | Preclinical |
| CHEMBL4871324 | 4.76 | IC50 | 17300.0 | Preclinical |
| CHEMBL4518197 | 4.73 | IC50 | 18800.0 | Preclinical |
| CHEMBL5268677 | 4.73 | IC50 | 18700.0 | Preclinical |
| CHEMBL5286133 | 4.7 | IC50 | 20000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 16 | 4.8 |