Use UniProt Q9H4L4 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5291568 Target Snapshot
Sentrin-specific protease 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9H4L4. Use UniProt Q9H4L4 as the stable identity anchor, then attach disease evidence before program review.
Sentrin-specific protease 3
Review this target as Sentrin-specific protease 3, mapped to UniProt Q9H4L4. Sequence length is 574 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Sentrin-specific protease 3 as ChEMBL target CHEMBL5291568, mapped to UniProt Q9H4L4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sentrin-specific protease 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9H4L4 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sentrin-specific protease 3 |
| UniProt Accession | Q9H4L4 |
| Component Type | Protein |
| Sequence Length | 574 aa |
Sentrin-specific protease 3
How to read this target
Review this target as Sentrin-specific protease 3, mapped to UniProt Q9H4L4. Sequence length is 574 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5287963 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL5175111 | 5.57 | IC50 | 2700.0 | Preclinical |
| CHEMBL5269877 | 5.47 | IC50 | 3400.0 | Preclinical |
| CHEMBL5276705 | 5.46 | IC50 | 3500.0 | Preclinical |
| CHEMBL5278967 | 5.34 | IC50 | 4600.0 | Preclinical |
| CHEMBL5290662 | 5.33 | IC50 | 4700.0 | Preclinical |
| CHEMBL5266367 | 5.32 | IC50 | 4800.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 7 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 7 | 5.5 |