Use UniProt P10739 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5291611 Target Snapshot
23S rRNA methylase leader peptide · SINGLE PROTEIN · Escherichia coli
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As of 2026-09-14Protein identity stays anchored to UniProt P10739. Use UniProt P10739 as the stable identity anchor, then attach disease evidence before program review.
23S rRNA methylase leader peptide
Review this target as 23S rRNA methylase leader peptide, mapped to UniProt P10739. Sequence length is 31 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 23S rRNA methylase leader peptide as ChEMBL target CHEMBL5291611, mapped to UniProt P10739. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 23S rRNA methylase leader peptide is the right protein anchor across sources, using UniProt P10739 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | 23S rRNA methylase leader peptide |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli |
| UniProt | P10739 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 23S rRNA methylase leader peptide |
| UniProt Accession | P10739 |
| Component Type | Protein |
| Sequence Length | 31 aa |
23S rRNA methylase leader peptide
How to read this target
Review this target as 23S rRNA methylase leader peptide, mapped to UniProt P10739. Sequence length is 31 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4165736 | 6.35 | IC50 | 450.0 | Preclinical |
| CHEMBL68738 | 4.2 | IC50 | 63000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 2 | 5.3 |