Alpha-glucosidase · PROTEIN FAMILY · Saccharomyces cerevisiae S288c
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P53341. Use UniProt P53341 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P53341 as the stable identity anchor, then attach disease evidence before program review.
Alpha-glucosidase MAL12
Review this target as Alpha-glucosidase, mapped to UniProt P53341. ChEMBL maps the protein component as Alpha-glucosidase MAL12. Sequence length is 584 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alpha-glucosidase as ChEMBL target CHEMBL5291954, mapped to UniProt P53341. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Alpha-glucosidase is the right protein anchor across sources, using UniProt P53341 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Alpha-glucosidase |
| Target Type | PROTEIN FAMILY |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P53341 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alpha-glucosidase MAL12 |
| UniProt Accession | P53341 |
| Component Type | Protein |
| Sequence Length | 584 aa |
Alpha-glucosidase MAL12
Review this target as Alpha-glucosidase, mapped to UniProt P53341. ChEMBL maps the protein component as Alpha-glucosidase MAL12. Sequence length is 584 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5402358 | 7.55 | IC50 | 28.47 | Preclinical |
| CHEMBL450152 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL5272219 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL5561939 | 6.82 | Ki | 150.0 | Preclinical |
| CHEMBL5561939 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL4435163 | 6.62 | IC50 | 240.0 | Preclinical |
| CHEMBL5647031 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL138007 | 6.38 | Ki | 420.0 | Preclinical |
| CHEMBL1467423 | 6.38 | Ki | 420.0 | Preclinical |
| CHEMBL5646841 | 6.14 | IC50 | 730.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 192 | 411 | 4.9 |