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Target Snapshot

CHEMBL5303569 Target Snapshot

GABA-A receptor; anion channel · PROTEIN COMPLEX GROUP · Canis lupus familiaris

0Compounds
0Assays
0Approved Drugs
0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt A0A8I3MM39. Use UniProt A0A8I3MM39 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt A0A8I3MM39 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Protein anchor
Gamma-aminobutyric acid receptor subunit alpha-1

Gamma-aminobutyric acid receptor subunit alpha-1

Review this target as GABA-A receptor; anion channel, mapped to UniProt A0A8I3MM39. ChEMBL maps the protein component as Gamma-aminobutyric acid receptor subunit alpha-1. Sequence length is 471 aa.

Protein source · UniProt accession via ChEMBL component mapping
UniProt A0A8I3MM39 Protein 471 aa
Open protein block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats GABA-A receptor; anion channel as ChEMBL target CHEMBL5303569, mapped to UniProt A0A8I3MM39. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
GABA-A receptor; anion channel
PROTEIN COMPLEX GROUP · Canis lupus familiaris
As of 2026-09-14
ChEMBL target ID
CHEMBL5303569
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
A0A8I3MM39
Gamma-aminobutyric acid receptor subunit alpha-1
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether GABA-A receptor; anion channel is the right protein anchor across sources, using UniProt A0A8I3MM39 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelGamma-aminobutyric acid receptor subunit alpha-1
UniProt AccessionA0A8I3MM39
Component TypeProtein
Sequence Length471 aa

Gamma-aminobutyric acid receptor subunit alpha-1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as GABA-A receptor; anion channel, mapped to UniProt A0A8I3MM39. ChEMBL maps the protein component as Gamma-aminobutyric acid receptor subunit alpha-1. Sequence length is 471 aa.

Mapped IDA0A8I3MM39
Review nameGABA-A receptor; anion channel
OrganismCanis lupus familiaris
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Source · ChEMBL 36 via Core Engine