Heat shock factor protein 1 · SINGLE PROTEIN · Mus musculus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P38532. Use UniProt P38532 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P38532 as the stable identity anchor, then attach disease evidence before program review.
Heat shock factor protein 1
Review this target as Heat shock factor protein 1, mapped to UniProt P38532. Sequence length is 525 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Heat shock factor protein 1 as ChEMBL target CHEMBL5313, mapped to UniProt P38532. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Heat shock factor protein 1 is the right protein anchor across sources, using UniProt P38532 as the stable mapping.
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| Preferred Name | Heat shock factor protein 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P38532 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Heat shock factor protein 1 |
| UniProt Accession | P38532 |
| Component Type | Protein |
| Sequence Length | 525 aa |
Heat shock factor protein 1
Review this target as Heat shock factor protein 1, mapped to UniProt P38532. Sequence length is 525 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3190911 | 6.8 | EC50 | 160.0 | Preclinical |
| CHEMBL1606031 | 6.78 | EC50 | 167.0 | Preclinical |
| CHEMBL3191218 | 6.78 | EC50 | 167.0 | Preclinical |
| CHEMBL1539980 | 6.74 | EC50 | 181.0 | Preclinical |
| CHEMBL1320007 | 6.72 | EC50 | 192.0 | Preclinical |
| CHEMBL1320794 | 6.72 | EC50 | 192.0 | Preclinical |
| CHEMBL1325943 | 6.68 | EC50 | 210.0 | Preclinical |
| CHEMBL1321335 | 6.67 | EC50 | 216.0 | Preclinical |
| CHEMBL1567793 | 6.67 | EC50 | 213.0 | Preclinical |
| CHEMBL1438842 | 6.62 | EC50 | 241.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 0 | — |
| single protein format | 2 | 0 | — |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 996 | 5.0 |