Tyrosine-protein kinase receptor TYRO3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q06418. Use UniProt Q06418 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q06418 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein kinase receptor TYRO3
Review this target as Tyrosine-protein kinase receptor TYRO3, mapped to UniProt Q06418. Sequence length is 890 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein kinase receptor TYRO3 as ChEMBL target CHEMBL5314, mapped to UniProt Q06418. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tyrosine-protein kinase receptor TYRO3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q06418 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase receptor TYRO3 |
| UniProt Accession | Q06418 |
| Component Type | Protein |
| Sequence Length | 890 aa |
Tyrosine-protein kinase receptor TYRO3
Review this target as Tyrosine-protein kinase receptor TYRO3, mapped to UniProt Q06418. Sequence length is 890 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5981096 | 11.0 | IC50 | 0.01 | Preclinical |
| CHEMBL5741930 | 10.92 | IC50 | 0.012 | Preclinical |
| CHEMBL5782595 | 10.92 | IC50 | 0.012 | Preclinical |
| CHEMBL5817527 | 10.92 | IC50 | 0.012 | Preclinical |
| CHEMBL5873205 | 10.92 | IC50 | 0.012 | Preclinical |
| CHEMBL5926926 | 10.39 | IC50 | 0.041 | Preclinical |
| CHEMBL6060115 | 10.39 | IC50 | 0.041 | Preclinical |
| CHEMBL5981781 | 10.28 | IC50 | 0.052 | Preclinical |
| CHEMBL5997590 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL5745182 | 10.01 | IC50 | 0.097 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 292 | 1,558 | 6.6 |
| assay format | 40 | 12 | 6.8 |
| cell-based format | 26 | 20 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 197 | 5.8 |
| cell-based format | 1 | 1 | 6.8 |