Epithelial discoidin domain-containing receptor 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q08345. Use UniProt Q08345 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q08345 as the stable identity anchor, then attach disease evidence before program review.
Epithelial discoidin domain-containing receptor 1
Review this target as Epithelial discoidin domain-containing receptor 1, mapped to UniProt Q08345. Sequence length is 913 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Epithelial discoidin domain-containing receptor 1 as ChEMBL target CHEMBL5319, mapped to UniProt Q08345. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Epithelial discoidin domain-containing receptor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q08345 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Epithelial discoidin domain-containing receptor 1 |
| UniProt Accession | Q08345 |
| Component Type | Protein |
| Sequence Length | 913 aa |
Epithelial discoidin domain-containing receptor 1
Review this target as Epithelial discoidin domain-containing receptor 1, mapped to UniProt Q08345. Sequence length is 913 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1230609 | 9.7 | Kd | 0.2 | Clinical |
| CHEMBL3907057 | 9.4 | Kd | 0.4 | Preclinical |
| CHEMBL5416410 | 9.3 | IC50 | 0.5 | Approved |
| CHEMBL2336015 | 9.22 | Kd | 0.6 | Preclinical |
| CHEMBL5416410 | 9.16 | Kd | 0.69 | Approved |
| CHEMBL574738 | 9.16 | Kd | 0.69 | Preclinical |
| CHEMBL4539920 | 9.15 | IC50 | 0.7078 | Preclinical |
| CHEMBL941 | 9.15 | Kd | 0.7 | Approved |
| CHEMBL3907057 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL255863 | 8.96 | Kd | 1.1 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 266 | 1,194 | 7.1 |
| assay format | 79 | 96 | 7.2 |
| cell-based format | 52 | 367 | 6.8 |
| subcellular format | 5 | 52 | 6.6 |