Non-receptor tyrosine-protein kinase TNK1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q13470. Use UniProt Q13470 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13470 as the stable identity anchor, then attach disease evidence before program review.
Non-receptor tyrosine-protein kinase TNK1
Review this target as Non-receptor tyrosine-protein kinase TNK1, mapped to UniProt Q13470. Sequence length is 666 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Non-receptor tyrosine-protein kinase TNK1 as ChEMBL target CHEMBL5334, mapped to UniProt Q13470. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Non-receptor tyrosine-protein kinase TNK1 is the right protein anchor across sources, using UniProt Q13470 as the stable mapping.
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| Preferred Name | Non-receptor tyrosine-protein kinase TNK1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13470 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Non-receptor tyrosine-protein kinase TNK1 |
| UniProt Accession | Q13470 |
| Component Type | Protein |
| Sequence Length | 666 aa |
Non-receptor tyrosine-protein kinase TNK1
Review this target as Non-receptor tyrosine-protein kinase TNK1, mapped to UniProt Q13470. Sequence length is 666 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.23 | IC50 | 0.584 | Preclinical |
| CHEMBL5772004 | 8.86 | IC50 | 1.37 | Preclinical |
| CHEMBL509032 | 8.74 | Kd | 1.8 | Preclinical |
| CHEMBL388978 | 8.6 | Kd | 2.5 | Preclinical |
| CHEMBL5756581 | 8.56 | IC50 | 2.77 | Preclinical |
| CHEMBL3545085 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL5853387 | 8.48 | IC50 | 3.33 | Preclinical |
| CHEMBL6022678 | 8.47 | IC50 | 3.36 | Preclinical |
| CHEMBL6058132 | 8.45 | IC50 | 3.59 | Preclinical |
| CHEMBL5993654 | 8.41 | IC50 | 3.92 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 114 | 141 | 7.4 |
| assay format | 25 | 3 | 8.0 |
| cell-based format | 8 | 1 | 5.0 |
| subcellular format | 6 | 39 | 6.5 |