Tyrosinase · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P11344. Use UniProt P11344 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11344 as the stable identity anchor, then attach disease evidence before program review.
Tyrosinase
Review this target as Tyrosinase, mapped to UniProt P11344. Sequence length is 533 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosinase as ChEMBL target CHEMBL5346, mapped to UniProt P11344. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Tyrosinase is the right protein anchor across sources, using UniProt P11344 as the stable mapping.
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| Preferred Name | Tyrosinase |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P11344 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosinase |
| UniProt Accession | P11344 |
| Component Type | Protein |
| Sequence Length | 533 aa |
Tyrosinase
Review this target as Tyrosinase, mapped to UniProt P11344. Sequence length is 533 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL278041 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL10 | 7.47 | IC50 | 34.0 | Preclinical |
| CHEMBL17331 | 7.05 | IC50 | 89.0 | Preclinical |
| CHEMBL221291 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL4063130 | 6.12 | IC50 | 750.0 | Preclinical |
| CHEMBL4445400 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL516671 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL3329471 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL43065 | 5.77 | IC50 | 1700.0 | Preclinical |
| CHEMBL263376 | 5.75 | IC50 | 1800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 140 | 48 | 5.1 |
| assay format | 28 | 0 | — |
| single protein format | 2 | 0 | — |