Use UniProt P11797 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5348 Target Snapshot
Chitinase B · SINGLE PROTEIN · Serratia marcescens
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As of 2026-09-14Protein identity stays anchored to UniProt P11797. Use UniProt P11797 as the stable identity anchor, then attach disease evidence before program review.
Chitinase B
Review this target as Chitinase B, mapped to UniProt P11797. Sequence length is 499 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Chitinase B as ChEMBL target CHEMBL5348, mapped to UniProt P11797. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Chitinase B is the right protein anchor across sources, using UniProt P11797 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Chitinase B |
| Target Type | SINGLE PROTEIN |
| Organism | Serratia marcescens |
| UniProt | P11797 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chitinase B |
| UniProt Accession | P11797 |
| Component Type | Protein |
| Sequence Length | 499 aa |
Chitinase B
How to read this target
Review this target as Chitinase B, mapped to UniProt P11797. Sequence length is 499 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL445236 | 8.47 | IC50 | 3.4 | Preclinical |
| CHEMBL5290116 | 8.38 | IC50 | 4.2 | Preclinical |
| CHEMBL5289869 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL4245260 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL3577620 | 7.44 | IC50 | 36.0 | Preclinical |
| CHEMBL1583158 | 7.24 | Ki | 58.0 | Preclinical |
| CHEMBL1230997 | 7.05 | IC50 | 90.0 | Preclinical |
| CHEMBL506684 | 7.04 | IC50 | 91.0 | Preclinical |
| CHEMBL197199 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL5276579 | 6.96 | IC50 | 110.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 14 assays, 50 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 45 | 6.0 |
| cell-based format | 5 | 5 | 6.8 |