Transcriptional activator protein LuxR · SINGLE PROTEIN · Aliivibrio fischeri
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As of 2026-09-14Protein identity stays anchored to UniProt P12746. Use UniProt P12746 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P12746 as the stable identity anchor, then attach disease evidence before program review.
Transcriptional activator protein LuxR
Review this target as Transcriptional activator protein LuxR, mapped to UniProt P12746. Sequence length is 250 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Transcriptional activator protein LuxR as ChEMBL target CHEMBL5351, mapped to UniProt P12746. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Transcriptional activator protein LuxR |
| Target Type | SINGLE PROTEIN |
| Organism | Aliivibrio fischeri |
| UniProt | P12746 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transcriptional activator protein LuxR |
| UniProt Accession | P12746 |
| Component Type | Protein |
| Sequence Length | 250 aa |
Transcriptional activator protein LuxR
Review this target as Transcriptional activator protein LuxR, mapped to UniProt P12746. Sequence length is 250 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1812080 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL4527540 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL4517457 | 6.6 | EC50 | 250.0 | Preclinical |
| CHEMBL1814832 | 6.51 | IC50 | 310.0 | Preclinical |
| CHEMBL1812089 | 6.46 | IC50 | 350.0 | Preclinical |
| CHEMBL1814829 | 6.46 | IC50 | 350.0 | Preclinical |
| CHEMBL405298 | 6.46 | EC50 | 350.0 | Preclinical |
| CHEMBL8799 | 6.4 | IC50 | 400.0 | Preclinical |
| CHEMBL1823931 | 6.35 | IC50 | 450.0 | Preclinical |
| CHEMBL4535946 | 6.3 | EC50 | 500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 26 | 68 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 45 | 5.2 |
| assay format | 5 | 4 | 4.1 |