Isocitrate lyase · SINGLE PROTEIN · Candida albicans
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As of 2026-09-14Protein identity stays anchored to UniProt Q9P8Q7. Use UniProt Q9P8Q7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9P8Q7 as the stable identity anchor, then attach disease evidence before program review.
Isocitrate lyase
Review this target as Isocitrate lyase, mapped to UniProt Q9P8Q7. Sequence length is 550 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Isocitrate lyase as ChEMBL target CHEMBL5359, mapped to UniProt Q9P8Q7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Isocitrate lyase |
| Target Type | SINGLE PROTEIN |
| Organism | Candida albicans |
| UniProt | Q9P8Q7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Isocitrate lyase |
| UniProt Accession | Q9P8Q7 |
| Component Type | Protein |
| Sequence Length | 550 aa |
Isocitrate lyase
Review this target as Isocitrate lyase, mapped to UniProt Q9P8Q7. Sequence length is 550 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1269936 | 5.58 | IC50 | 2650.0 | Preclinical |
| CHEMBL1818099 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL451226 | 5.22 | IC50 | 6000.0 | Preclinical |
| CHEMBL2204152 | 5.12 | IC50 | 7620.0 | Preclinical |
| CHEMBL1269421 | 5.05 | IC50 | 8890.0 | Preclinical |
| CHEMBL2204157 | 4.99 | IC50 | 10360.0 | Preclinical |
| CHEMBL2204151 | 4.96 | IC50 | 11000.0 | Preclinical |
| CHEMBL1269935 | 4.93 | IC50 | 11630.0 | Preclinical |
| CHEMBL2047351 | 4.93 | IC50 | 11820.0 | Preclinical |
| CHEMBL1270043 | 4.83 | IC50 | 14770.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 16 | 76 | 4.5 |