Broad substrate specificity ATP-binding cassette transporter ABCG2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9UNQ0. Use UniProt Q9UNQ0 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UNQ0 as the stable identity anchor, then attach disease evidence before program review.
Broad substrate specificity ATP-binding cassette transporter ABCG2
Review this target as Broad substrate specificity ATP-binding cassette transporter ABCG2, mapped to UniProt Q9UNQ0. Sequence length is 655 aa.
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This review treats Broad substrate specificity ATP-binding cassette transporter ABCG2 as ChEMBL target CHEMBL5393, mapped to UniProt Q9UNQ0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Broad substrate specificity ATP-binding cassette transporter ABCG2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UNQ0 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Broad substrate specificity ATP-binding cassette transporter ABCG2 |
| UniProt Accession | Q9UNQ0 |
| Component Type | Protein |
| Sequence Length | 655 aa |
Broad substrate specificity ATP-binding cassette transporter ABCG2
Review this target as Broad substrate specificity ATP-binding cassette transporter ABCG2, mapped to UniProt Q9UNQ0. Sequence length is 655 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2141796 | 10.99 | EC50 | 0.01019 | Preclinical |
| CHEMBL2145384 | 10.99 | EC50 | 0.01013 | Preclinical |
| CHEMBL2142245 | 10.96 | EC50 | 0.01088 | Preclinical |
| CHEMBL2137928 | 10.92 | EC50 | 0.01209 | Preclinical |
| CHEMBL2141666 | 10.64 | EC50 | 0.02297 | Preclinical |
| CHEMBL2130718 | 10.63 | EC50 | 0.02338 | Preclinical |
| CHEMBL2137680 | 10.39 | EC50 | 0.04093 | Preclinical |
| CHEMBL2140166 | 10.39 | EC50 | 0.04032 | Preclinical |
| CHEMBL2135227 | 10.35 | EC50 | 0.04419 | Preclinical |
| CHEMBL2133727 | 10.32 | EC50 | 0.04775 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 506 | 1,204 | 6.2 |
| single protein format | 60 | 61 | 6.3 |
| assay format | 50 | 87 | 7.1 |
| cell membrane format | 18 | 44 | 5.6 |
| tissue-based format | 6 | 18 | 6.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 91 | 1 | 5.6 |
| single protein format | 17 | 3 | 4.8 |
| assay format | 2 | 2 | 4.8 |
| cell membrane format | 2 | 0 | — |
| mitochondrion format | 2 | 0 | — |
| tissue-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 74 | 13 | 5.9 |
| cell membrane format | 33 | 4 | 5.9 |
| assay format | 4 | 112 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 1 | 4 | 4.6 |