Calmodulin-sensitive adenylate cyclase · SINGLE PROTEIN · Bacillus anthracis
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As of 2026-09-14Protein identity stays anchored to UniProt P40136. Use UniProt P40136 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P40136 as the stable identity anchor, then attach disease evidence before program review.
Calmodulin-sensitive adenylate cyclase
Review this target as Calmodulin-sensitive adenylate cyclase, mapped to UniProt P40136. Sequence length is 800 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Calmodulin-sensitive adenylate cyclase as ChEMBL target CHEMBL5396, mapped to UniProt P40136. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Calmodulin-sensitive adenylate cyclase |
| Target Type | SINGLE PROTEIN |
| Organism | Bacillus anthracis |
| UniProt | P40136 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Calmodulin-sensitive adenylate cyclase |
| UniProt Accession | P40136 |
| Component Type | Protein |
| Sequence Length | 800 aa |
Calmodulin-sensitive adenylate cyclase
Review this target as Calmodulin-sensitive adenylate cyclase, mapped to UniProt P40136. Sequence length is 800 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1162433 | 7.87 | IC50 | 13.5 | Preclinical |
| CHEMBL5415520 | 7.29 | IC50 | 50.8 | Preclinical |
| CHEMBL5419412 | 7.05 | IC50 | 88.4 | Preclinical |
| CHEMBL594333 | 7.0 | Ki | 100.0 | Preclinical |
| CHEMBL5401885 | 6.97 | IC50 | 108.0 | Preclinical |
| CHEMBL4853492 | 6.63 | IC50 | 235.0 | Preclinical |
| CHEMBL4218073 | 6.52 | Ki | 300.0 | Preclinical |
| CHEMBL4855382 | 6.37 | IC50 | 428.0 | Preclinical |
| CHEMBL4206295 | 6.16 | Ki | 700.0 | Preclinical |
| CHEMBL4848421 | 6.15 | IC50 | 704.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 37 | 5.5 |
| cell-based format | 6 | 29 | 5.0 |