Histone-arginine methyltransferase CARM1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q86X55. Use UniProt Q86X55 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q86X55 as the stable identity anchor, then attach disease evidence before program review.
Histone-arginine methyltransferase CARM1
Review this target as Histone-arginine methyltransferase CARM1, mapped to UniProt Q86X55. Sequence length is 608 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone-arginine methyltransferase CARM1 as ChEMBL target CHEMBL5406, mapped to UniProt Q86X55. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Histone-arginine methyltransferase CARM1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q86X55 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone-arginine methyltransferase CARM1 |
| UniProt Accession | Q86X55 |
| Component Type | Protein |
| Sequence Length | 608 aa |
Histone-arginine methyltransferase CARM1
Review this target as Histone-arginine methyltransferase CARM1, mapped to UniProt Q86X55. Sequence length is 608 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4436627 | 10.3 | IC50 | 0.05 | Preclinical |
| CHEMBL584335 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL571829 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL571639 | 9.59 | IC50 | 0.26 | Preclinical |
| CHEMBL572103 | 9.39 | IC50 | 0.41 | Preclinical |
| CHEMBL5272699 | 9.19 | IC50 | 0.65 | Preclinical |
| CHEMBL571431 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL5270700 | 9.11 | IC50 | 0.78 | Preclinical |
| CHEMBL572102 | 9.08 | IC50 | 0.84 | Preclinical |
| CHEMBL5274219 | 9.04 | IC50 | 0.92 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 162 | 68 | 6.7 |
| single protein format | 158 | 267 | 6.9 |
| assay format | 8 | 8 | 4.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 4 | 8.1 |
| cell-based format | 2 | 1 | 6.4 |