SRSF protein kinase 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9UPE1. Use UniProt Q9UPE1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UPE1 as the stable identity anchor, then attach disease evidence before program review.
SRSF protein kinase 3
Review this target as SRSF protein kinase 3, mapped to UniProt Q9UPE1. Sequence length is 567 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats SRSF protein kinase 3 as ChEMBL target CHEMBL5415, mapped to UniProt Q9UPE1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | SRSF protein kinase 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UPE1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | SRSF protein kinase 3 |
| UniProt Accession | Q9UPE1 |
| Component Type | Protein |
| Sequence Length | 567 aa |
SRSF protein kinase 3
Review this target as SRSF protein kinase 3, mapped to UniProt Q9UPE1. Sequence length is 567 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5085558 | 9.23 | IC50 | 0.59 | Preclinical |
| CHEMBL4468747 | 8.32 | IC50 | 4.81 | Preclinical |
| CHEMBL502835 | 7.92 | Kd | 12.0 | Approved |
| CHEMBL603469 | 7.89 | Kd | 13.0 | Clinical |
| CHEMBL5085558 | 7.7 | EC50 | 20.0 | Preclinical |
| CHEMBL4064277 | 7.57 | IC50 | 27.0 | Preclinical |
| CHEMBL535 | 7.23 | Kd | 59.0 | Approved |
| CHEMBL388978 | 7.14 | Kd | 73.0 | Preclinical |
| CHEMBL608533 | 7.1 | Kd | 80.0 | Approved |
| CHEMBL1721885 | 6.92 | Kd | 120.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 177 | 33 | 6.5 |
| assay format | 37 | 0 | — |
| cell-based format | 11 | 3 | 6.8 |
| subcellular format | 2 | 2 | 6.3 |