Cyclin-dependent kinase 11A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UQ88. Use UniProt Q9UQ88 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UQ88 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 11A
Review this target as Cyclin-dependent kinase 11A, mapped to UniProt Q9UQ88. Sequence length is 783 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclin-dependent kinase 11A as ChEMBL target CHEMBL5416, mapped to UniProt Q9UQ88. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cyclin-dependent kinase 11A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UQ88 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 11A |
| UniProt Accession | Q9UQ88 |
| Component Type | Protein |
| Sequence Length | 783 aa |
Cyclin-dependent kinase 11A
Review this target as Cyclin-dependent kinase 11A, mapped to UniProt Q9UQ88. Sequence length is 783 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4455382 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL445813 | 8.28 | Kd | 5.2 | Clinical |
| CHEMBL1989043 | 7.48 | Kd | 33.0 | Preclinical |
| CHEMBL5185990 | 7.42 | Kd | 38.0 | Preclinical |
| CHEMBL5175800 | 7.41 | Kd | 39.0 | Preclinical |
| CHEMBL5185655 | 7.37 | Kd | 43.0 | Preclinical |
| CHEMBL296468 | 7.32 | Kd | 48.0 | Preclinical |
| CHEMBL5200963 | 7.31 | Kd | 49.0 | Preclinical |
| CHEMBL5180190 | 7.16 | Kd | 69.0 | Preclinical |
| CHEMBL5184522 | 7.0 | Kd | 99.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 72 | 19 | 6.4 |
| assay format | 16 | 22 | 6.6 |
| subcellular format | 10 | 0 | — |
| cell-based format | 7 | 25 | 6.1 |