Use UniProt P06935 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5419 Target Snapshot
Genome polyprotein · SINGLE PROTEIN · West Nile virus
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As of 2026-09-13Protein identity stays anchored to UniProt P06935. Use UniProt P06935 as the stable identity anchor, then attach disease evidence before program review.
Genome polyprotein
Review this target as Genome polyprotein, mapped to UniProt P06935. Sequence length is 3430 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Genome polyprotein as ChEMBL target CHEMBL5419, mapped to UniProt P06935. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Genome polyprotein is the right protein anchor across sources, using UniProt P06935 as the stable mapping.
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| Preferred Name | Genome polyprotein |
| Target Type | SINGLE PROTEIN |
| Organism | West Nile virus |
| UniProt | P06935 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Genome polyprotein |
| UniProt Accession | P06935 |
| Component Type | Protein |
| Sequence Length | 3430 aa |
Genome polyprotein
How to read this target
Review this target as Genome polyprotein, mapped to UniProt P06935. Sequence length is 3430 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL506092 | 8.22 | Ki | 6.0 | Preclinical |
| CHEMBL522355 | 8.05 | Ki | 9.0 | Preclinical |
| CHEMBL492866 | 7.96 | Ki | 11.0 | Preclinical |
| CHEMBL459944 | 7.89 | Ki | 13.0 | Preclinical |
| CHEMBL522831 | 7.72 | Ki | 19.0 | Preclinical |
| CHEMBL503904 | 7.7 | Ki | 20.0 | Preclinical |
| CHEMBL492867 | 7.58 | Ki | 26.0 | Preclinical |
| CHEMBL494923 | 7.55 | Ki | 28.0 | Preclinical |
| CHEMBL506092 | 7.5 | IC50 | 32.0 | Preclinical |
| CHEMBL523197 | 7.4 | Ki | 40.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 73 assays, 182 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 46 | 108 | 5.7 |
| cell-based format | 17 | 55 | 5.5 |
| assay format | 10 | 19 | 5.2 |