Myosin light chain kinase family member 4 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q86YV6. Use UniProt Q86YV6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q86YV6 as the stable identity anchor, then attach disease evidence before program review.
Myosin light chain kinase family member 4
Review this target as Myosin light chain kinase family member 4, mapped to UniProt Q86YV6. Sequence length is 388 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Myosin light chain kinase family member 4 as ChEMBL target CHEMBL5426, mapped to UniProt Q86YV6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Myosin light chain kinase family member 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q86YV6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Myosin light chain kinase family member 4 |
| UniProt Accession | Q86YV6 |
| Component Type | Protein |
| Sequence Length | 388 aa |
Myosin light chain kinase family member 4
Review this target as Myosin light chain kinase family member 4, mapped to UniProt Q86YV6. Sequence length is 388 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5574990 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5569176 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL5564156 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL5569603 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL5565459 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL535 | 7.82 | Kd | 15.0 | Approved |
| CHEMBL5575519 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL5542886 | 7.57 | IC50 | 27.0 | Preclinical |
| CHEMBL603469 | 7.54 | Kd | 29.0 | Clinical |
| CHEMBL1721885 | 7.5 | Kd | 32.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 86 | 51 | 6.8 |
| assay format | 21 | 2 | 5.7 |
| cell-based format | 3 | 2 | 5.8 |