Mu-opioid receptor · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8CGM4. Use UniProt Q8CGM4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8CGM4 as the stable identity anchor, then attach disease evidence before program review.
Mu-type opioid receptor
Review this target as Mu-opioid receptor, mapped to UniProt Q8CGM4. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 400 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mu-opioid receptor as ChEMBL target CHEMBL5430, mapped to UniProt Q8CGM4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Mu-opioid receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | Q8CGM4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mu-type opioid receptor |
| UniProt Accession | Q8CGM4 |
| Component Type | Protein |
| Sequence Length | 400 aa |
Mu-type opioid receptor
Review this target as Mu-opioid receptor, mapped to UniProt Q8CGM4. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 400 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL442577 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL109390 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL444197 | 8.92 | IC50 | 1.21 | Preclinical |
| CHEMBL501451 | 8.52 | IC50 | 3.02 | Preclinical |
| CHEMBL235109 | 8.07 | IC50 | 8.5 | Preclinical |
| CHEMBL333357 | 8.02 | IC50 | 9.67 | Preclinical |
| CHEMBL522293 | 7.53 | IC50 | 29.3 | Preclinical |
| CHEMBL361922 | 7.38 | IC50 | 42.1 | Preclinical |
| CHEMBL235107 | 7.33 | IC50 | 47.0 | Preclinical |
| CHEMBL235743 | 7.33 | IC50 | 47.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 3 | 13 | 7.6 |
| assay format | 1 | 7 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 1 | 0 | — |