Use UniProt O60939 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5446 Target Snapshot
Sodium channel regulatory subunit beta-2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O60939. Use UniProt O60939 as the stable identity anchor, then attach disease evidence before program review.
Sodium channel regulatory subunit beta-2
Review this target as Sodium channel regulatory subunit beta-2, mapped to UniProt O60939. Sequence length is 215 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Sodium channel regulatory subunit beta-2 as ChEMBL target CHEMBL5446, mapped to UniProt O60939. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Sodium channel regulatory subunit beta-2 is the right protein anchor across sources, using UniProt O60939 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Sodium channel regulatory subunit beta-2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O60939 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium channel regulatory subunit beta-2 |
| UniProt Accession | O60939 |
| Component Type | Protein |
| Sequence Length | 215 aa |
Sodium channel regulatory subunit beta-2
How to read this target
Review this target as Sodium channel regulatory subunit beta-2, mapped to UniProt O60939. Sequence length is 215 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3609749 | 6.0 | IC50 | 1000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 1 | 6.0 |