Heat shock 70 kDa protein 1A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P0DMV8. Use UniProt P0DMV8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P0DMV8 as the stable identity anchor, then attach disease evidence before program review.
Heat shock 70 kDa protein 1A
Review this target as Heat shock 70 kDa protein 1A, mapped to UniProt P0DMV8. Sequence length is 641 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Heat shock 70 kDa protein 1A as ChEMBL target CHEMBL5460, mapped to UniProt P0DMV8. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Heat shock 70 kDa protein 1A is the right protein anchor across sources, using UniProt P0DMV8 as the stable mapping.
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| Preferred Name | Heat shock 70 kDa protein 1A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P0DMV8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Heat shock 70 kDa protein 1A |
| UniProt Accession | P0DMV8 |
| Component Type | Protein |
| Sequence Length | 641 aa |
Heat shock 70 kDa protein 1A
Review this target as Heat shock 70 kDa protein 1A, mapped to UniProt P0DMV8. Sequence length is 641 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1232461 | 7.15 | Kd | 71.0 | Clinical |
| CHEMBL1232461 | 6.82 | IC50 | 150.0 | Clinical |
| CHEMBL502775 | 6.48 | IC50 | 332.0 | Preclinical |
| CHEMBL1481974 | 6.24 | IC50 | 578.0 | Preclinical |
| CHEMBL471004 | 6.2 | IC50 | 634.0 | Preclinical |
| CHEMBL6246 | 6.12 | IC50 | 760.0 | Clinical |
| CHEMBL5639838 | 5.79 | Kd | 1630.0 | Preclinical |
| CHEMBL1409373 | 5.71 | IC50 | 1970.0 | Preclinical |
| CHEMBL244695 | 5.62 | IC50 | 2420.0 | Preclinical |
| CHEMBL1363132 | 5.5 | IC50 | 3130.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 19 | 47 | 5.0 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |