Use UniProt P08134 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5465545 Target Snapshot
Rho-related GTP-binding protein RhoC · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P08134. Use UniProt P08134 as the stable identity anchor, then attach disease evidence before program review.
Rho-related GTP-binding protein RhoC
Review this target as Rho-related GTP-binding protein RhoC, mapped to UniProt P08134. Sequence length is 193 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Rho-related GTP-binding protein RhoC as ChEMBL target CHEMBL5465545, mapped to UniProt P08134. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Rho-related GTP-binding protein RhoC is the right protein anchor across sources, using UniProt P08134 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Rho-related GTP-binding protein RhoC |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P08134 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Rho-related GTP-binding protein RhoC |
| UniProt Accession | P08134 |
| Component Type | Protein |
| Sequence Length | 193 aa |
Rho-related GTP-binding protein RhoC
How to read this target
Review this target as Rho-related GTP-binding protein RhoC, mapped to UniProt P08134. Sequence length is 193 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1487 | 5.3 | IC50 | 5000.0 | Approved |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 5.3 |