Galectin-8 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt O00214. Use UniProt O00214 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O00214 as the stable identity anchor, then attach disease evidence before program review.
Galectin-8
Review this target as Galectin-8, mapped to UniProt O00214. Sequence length is 317 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Galectin-8 as ChEMBL target CHEMBL5475, mapped to UniProt O00214. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Galectin-8 is the right protein anchor across sources, using UniProt O00214 as the stable mapping.
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| Preferred Name | Galectin-8 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O00214 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Galectin-8 |
| UniProt Accession | O00214 |
| Component Type | Protein |
| Sequence Length | 317 aa |
Galectin-8
Review this target as Galectin-8, mapped to UniProt O00214. Sequence length is 317 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1669631 | 9.64 | Kd | 0.23 | Preclinical |
| CHEMBL1669628 | 8.81 | Kd | 1.55 | Preclinical |
| CHEMBL1669630 | 7.51 | Kd | 31.0 | Preclinical |
| CHEMBL4854378 | 5.82 | Kd | 1500.0 | Preclinical |
| CHEMBL4858277 | 5.75 | Kd | 1800.0 | Preclinical |
| CHEMBL5436399 | 5.7 | Kd | 2010.0 | Preclinical |
| CHEMBL5421354 | 5.69 | Kd | 2060.0 | Preclinical |
| CHEMBL3764379 | 5.64 | Kd | 2300.0 | Preclinical |
| CHEMBL4872829 | 5.55 | Kd | 2800.0 | Preclinical |
| CHEMBL5436190 | 5.25 | Kd | 5600.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 28 | 89 | 5.3 |
| cell-based format | 21 | 36 | 4.8 |
| assay format | 8 | 18 | 4.2 |