SKP1-SKP2-CKS1 · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P61024. Use UniProt P61024 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P61024 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinases regulatory subunit 1
Review this target as SKP1-SKP2-CKS1, mapped to UniProt P61024. ChEMBL maps the protein component as Cyclin-dependent kinases regulatory subunit 1. Sequence length is 79 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats SKP1-SKP2-CKS1 as ChEMBL target CHEMBL5482973, mapped to UniProt P61024. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | SKP1-SKP2-CKS1 |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | P61024 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinases regulatory subunit 1 |
| UniProt Accession | P61024 |
| Component Type | Protein |
| Sequence Length | 79 aa |
Cyclin-dependent kinases regulatory subunit 1
Review this target as SKP1-SKP2-CKS1, mapped to UniProt P61024. ChEMBL maps the protein component as Cyclin-dependent kinases regulatory subunit 1. Sequence length is 79 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5411495 | 6.24 | IC50 | 570.0 | Preclinical |
| CHEMBL5420161 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL5393726 | 5.77 | IC50 | 1700.0 | Preclinical |
| CHEMBL5420913 | 5.64 | IC50 | 2300.0 | Preclinical |
| CHEMBL5406988 | 5.62 | IC50 | 2400.0 | Preclinical |
| CHEMBL5428364 | 5.62 | IC50 | 2400.0 | Preclinical |
| CHEMBL5399928 | 5.57 | IC50 | 2700.0 | Preclinical |
| CHEMBL5410031 | 5.55 | IC50 | 2800.0 | Preclinical |
| CHEMBL5417549 | 5.55 | IC50 | 2800.0 | Preclinical |
| CHEMBL5427761 | 5.48 | IC50 | 3300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 2 | 37 | 5.1 |