5-hydroxytryptamine receptor 7 · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt P50407. Use UniProt P50407 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P50407 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 7
Review this target as 5-hydroxytryptamine receptor 7, mapped to UniProt P50407. Sequence length is 446 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 5-hydroxytryptamine receptor 7 as ChEMBL target CHEMBL5494, mapped to UniProt P50407. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 5-hydroxytryptamine receptor 7 is the right protein anchor across sources, using UniProt P50407 as the stable mapping.
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| Preferred Name | 5-hydroxytryptamine receptor 7 |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | P50407 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 7 |
| UniProt Accession | P50407 |
| Component Type | Protein |
| Sequence Length | 446 aa |
5-hydroxytryptamine receptor 7
Review this target as 5-hydroxytryptamine receptor 7, mapped to UniProt P50407. Sequence length is 446 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL282199 | 8.4 | Kd | 3.981 | Preclinical |
| CHEMBL244161 | 7.7 | Kd | 19.95 | Preclinical |
| CHEMBL494709 | 6.51 | EC50 | 310.0 | Preclinical |
| CHEMBL492480 | 6.31 | EC50 | 490.0 | Preclinical |
| CHEMBL522691 | 6.22 | EC50 | 600.0 | Preclinical |
| CHEMBL18840 | 6.2 | EC50 | 630.0 | Preclinical |
| CHEMBL243744 | 6.05 | EC50 | 900.0 | Preclinical |
| CHEMBL243955 | 5.93 | EC50 | 1170.0 | Preclinical |
| CHEMBL243954 | 5.75 | EC50 | 1770.0 | Preclinical |
| CHEMBL222188 | 5.1 | EC50 | 8000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 27 | 13 | 6.9 |