Start with Coagulation Protein Disorders, then reuse UniProt P07225 as the stable protein anchor across project notes and exports.
CHEMBL5498501 Target Snapshot
Vitamin K-dependent protein S · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Vitamin K-dependent protein S shows approved-linked disease relevance led by Coagulation Protein Disorders. 1 more disease program remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt P07225. Start with Coagulation Protein Disorders, then reuse UniProt P07225 as the stable protein anchor across project notes and exports.
Vitamin K-dependent protein S shows approved-linked disease relevance led by Coagulation Protein Disorders. 1 more disease program remain visible in the same review block. 1 linked drug remains visible in the same block.
Start review with Coagulation Protein Disorders because it currently carries approved-linked support. Linked drugs include PROTEIN S HUMAN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyVitamin K-dependent protein S
Review this target as Vitamin K-dependent protein S, mapped to UniProt P07225. Sequence length is 676 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Vitamin K-dependent protein S as ChEMBL target CHEMBL5498501, mapped to UniProt P07225. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Vitamin K-dependent protein S is the right protein anchor across sources, using UniProt P07225 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why Coagulation Protein Disorders is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.
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Open Review-ready CardBasic Information
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| Preferred Name | Vitamin K-dependent protein S |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P07225 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Vitamin K-dependent protein S |
| UniProt Accession | P07225 |
| Component Type | Protein |
| Sequence Length | 676 aa |
Vitamin K-dependent protein S
How to read this target
Review this target as Vitamin K-dependent protein S, mapped to UniProt P07225. Sequence length is 676 aa.
Disease Relevance & Evidence Level
Open Targets-ready disease context using the current target-indication evidence contract.
Vitamin K-dependent protein S shows approved-linked disease relevance led by Coagulation Protein Disorders. 1 more disease program remain visible in the same review block.
How to read disease relevance
Start review with Coagulation Protein Disorders because it currently carries approved-linked support. Linked drugs include PROTEIN S HUMAN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.