Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL5498504 Target Snapshot

Dystrophin · SINGLE PROTEIN · Homo sapiens

0Compounds
0Assays
0Approved Drugs
0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Dystrophin shows approved-linked disease relevance led by Becker muscular dystrophy. 1 more disease program remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt P11532. Start with Becker muscular dystrophy, then reuse UniProt P11532 as the stable protein anchor across project notes and exports.

Review focus
Review-ready target frame

Start with Becker muscular dystrophy, then reuse UniProt P11532 as the stable protein anchor across project notes and exports.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13 1 linked drug
Open source guide
Disease program
Becker muscular dystrophy

Dystrophin shows approved-linked disease relevance led by Becker muscular dystrophy. 1 more disease program remain visible in the same review block. 1 linked drug remains visible in the same block.

Start review with Becker muscular dystrophy because it currently carries approved-linked support. Linked drugs include DELANDISTROGENE MOXEPARVOVEC. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 1 linked drug
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Dystrophin as ChEMBL target CHEMBL5498504, mapped to UniProt P11532. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Dystrophin
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL5498504
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P11532
Dystrophin
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Dystrophin is the right protein anchor across sources, using UniProt P11532 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why Becker muscular dystrophy is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelDystrophin
UniProt AccessionP11532
Component TypeProtein
Sequence Length3685 aa

Dystrophin

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Dystrophin, mapped to UniProt P11532. Sequence length is 3685 aa.

Mapped IDP11532
Review nameDystrophin
OrganismHomo sapiens
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

Dystrophin shows approved-linked disease relevance led by Becker muscular dystrophy. 1 more disease program remain visible in the same review block.

Approved-linked Approved
Becker muscular dystrophy
1 linked drug · 1 direct · 1 efficacy
Linked drugDELANDISTROGENE MOXEPARVOVEC
Approved-linked Approved
Duchenne muscular dystrophy
1 linked drug · 1 direct · 1 efficacy
Linked drugDELANDISTROGENE MOXEPARVOVEC
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with Becker muscular dystrophy because it currently carries approved-linked support. Linked drugs include DELANDISTROGENE MOXEPARVOVEC. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseaseBecker muscular dystrophy
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Source · ChEMBL 36 via Core Engine