Histone acetyltransferase KAT2B · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q92831. Use UniProt Q92831 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q92831 as the stable identity anchor, then attach disease evidence before program review.
Histone acetyltransferase KAT2B
Review this target as Histone acetyltransferase KAT2B, mapped to UniProt Q92831. Sequence length is 832 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone acetyltransferase KAT2B as ChEMBL target CHEMBL5500, mapped to UniProt Q92831. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Histone acetyltransferase KAT2B is the right protein anchor across sources, using UniProt Q92831 as the stable mapping.
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| Preferred Name | Histone acetyltransferase KAT2B |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q92831 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone acetyltransferase KAT2B |
| UniProt Accession | Q92831 |
| Component Type | Protein |
| Sequence Length | 832 aa |
Histone acetyltransferase KAT2B
Review this target as Histone acetyltransferase KAT2B, mapped to UniProt Q92831. Sequence length is 832 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4069412 | 8.9 | Ki | 1.259 | Preclinical |
| CHEMBL4574669 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL4543497 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL4872300 | 7.92 | Kd | 12.0 | Preclinical |
| CHEMBL4103402 | 7.9 | IC50 | 12.7 | Preclinical |
| CHEMBL4449143 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL4861491 | 7.85 | Kd | 14.0 | Preclinical |
| CHEMBL4439202 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL4067343 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL4216214 | 7.72 | IC50 | 19.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 114 | 300 | 6.2 |
| assay format | 65 | 84 | 5.4 |
| cell-based format | 27 | 15 | 5.4 |