Histone acetyltransferase KAT2A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q92830. Use UniProt Q92830 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q92830 as the stable identity anchor, then attach disease evidence before program review.
Histone acetyltransferase KAT2A
Review this target as Histone acetyltransferase KAT2A, mapped to UniProt Q92830. Sequence length is 837 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone acetyltransferase KAT2A as ChEMBL target CHEMBL5501, mapped to UniProt Q92830. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Histone acetyltransferase KAT2A is the right protein anchor across sources, using UniProt Q92830 as the stable mapping.
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| Preferred Name | Histone acetyltransferase KAT2A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q92830 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone acetyltransferase KAT2A |
| UniProt Accession | Q92830 |
| Component Type | Protein |
| Sequence Length | 837 aa |
Histone acetyltransferase KAT2A
Review this target as Histone acetyltransferase KAT2A, mapped to UniProt Q92830. Sequence length is 837 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4069412 | 8.9 | Ki | 1.259 | Preclinical |
| CHEMBL4872300 | 7.36 | Kd | 44.0 | Preclinical |
| CHEMBL4780673 | 7.21 | Kd | 62.0 | Preclinical |
| CHEMBL4574669 | 6.98 | Kd | 105.0 | Preclinical |
| CHEMBL4465880 | 6.8 | Kd | 158.49 | Preclinical |
| CHEMBL5289762 | 6.8 | Kd | 160.0 | Preclinical |
| CHEMBL4570969 | 6.66 | IC50 | 220.0 | Preclinical |
| CHEMBL4449894 | 6.6 | Kd | 251.19 | Preclinical |
| CHEMBL5282240 | 6.39 | Kd | 410.0 | Preclinical |
| CHEMBL4577486 | 6.3 | Kd | 501.19 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 65 | 41 | 5.0 |
| assay format | 24 | 7 | 6.8 |
| cell-based format | 11 | 3 | 4.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |