Casein kinase I isoform alpha-like · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q8N752. Use UniProt Q8N752 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8N752 as the stable identity anchor, then attach disease evidence before program review.
Casein kinase I isoform alpha-like
Review this target as Casein kinase I isoform alpha-like, mapped to UniProt Q8N752. Sequence length is 337 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Casein kinase I isoform alpha-like as ChEMBL target CHEMBL5520, mapped to UniProt Q8N752. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Casein kinase I isoform alpha-like is the right protein anchor across sources, using UniProt Q8N752 as the stable mapping.
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| Preferred Name | Casein kinase I isoform alpha-like |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8N752 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Casein kinase I isoform alpha-like |
| UniProt Accession | Q8N752 |
| Component Type | Protein |
| Sequence Length | 337 aa |
Casein kinase I isoform alpha-like
Review this target as Casein kinase I isoform alpha-like, mapped to UniProt Q8N752. Sequence length is 337 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 6.6 | Kd | 250.0 | Preclinical |
| CHEMBL5303449 | 6.28 | IC50 | 520.0 | Preclinical |
| CHEMBL535 | 6.26 | Kd | 550.0 | Approved |
| CHEMBL4088216 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4097778 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4549667 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL607707 | 6.0 | Kd | 1000.0 | Clinical |
| CHEMBL388978 | 5.9 | IC50 | 1270.0 | Preclinical |
| CHEMBL1721885 | 5.82 | Kd | 1500.0 | Clinical |
| CHEMBL10 | 5.77 | Kd | 1700.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 71 | 19 | 5.8 |
| assay format | 19 | 0 | — |
| cell-based format | 1 | 0 | — |