Potassium voltage-gated channel subfamily KQT member 2 · SINGLE PROTEIN · Rattus norvegicus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt O88943. Use UniProt O88943 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O88943 as the stable identity anchor, then attach disease evidence before program review.
Potassium voltage-gated channel subfamily KQT member 2
Review this target as Potassium voltage-gated channel subfamily KQT member 2, mapped to UniProt O88943. Sequence length is 852 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Potassium voltage-gated channel subfamily KQT member 2 as ChEMBL target CHEMBL5530, mapped to UniProt O88943. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Potassium voltage-gated channel subfamily KQT member 2 is the right protein anchor across sources, using UniProt O88943 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Potassium voltage-gated channel subfamily KQT member 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | O88943 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium voltage-gated channel subfamily KQT member 2 |
| UniProt Accession | O88943 |
| Component Type | Protein |
| Sequence Length | 852 aa |
Potassium voltage-gated channel subfamily KQT member 2
Review this target as Potassium voltage-gated channel subfamily KQT member 2, mapped to UniProt O88943. Sequence length is 852 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5180351 | 7.43 | EC50 | 36.98 | Preclinical |
| CHEMBL1306085 | 6.77 | EC50 | 170.0 | Preclinical |
| CHEMBL1432943 | 6.04 | EC50 | 920.0 | Preclinical |
| CHEMBL1454208 | 5.84 | EC50 | 1460.0 | Preclinical |
| CHEMBL1556939 | 5.82 | EC50 | 1510.0 | Preclinical |
| CHEMBL1356888 | 5.78 | EC50 | 1650.0 | Preclinical |
| CHEMBL1421441 | 5.74 | EC50 | 1830.0 | Preclinical |
| CHEMBL1563514 | 5.71 | EC50 | 1970.0 | Preclinical |
| CHEMBL41355 | 5.69 | EC50 | 2040.0 | Approved |
| CHEMBL1577624 | 5.66 | EC50 | 2170.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 13 | 2 | 6.6 |
| single protein format | 3 | 0 | — |
| cell membrane format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 7 | 4 | 5.4 |
| cell-based format | 1 | 36 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 1 | 5.7 |