Use UniProt Q43077 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5534 Target Snapshot
Primary amine oxidase · SINGLE PROTEIN · Pisum sativum
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As of 2026-09-14Protein identity stays anchored to UniProt Q43077. Use UniProt Q43077 as the stable identity anchor, then attach disease evidence before program review.
Primary amine oxidase
Review this target as Primary amine oxidase, mapped to UniProt Q43077. Sequence length is 674 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Primary amine oxidase as ChEMBL target CHEMBL5534, mapped to UniProt Q43077. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Primary amine oxidase is the right protein anchor across sources, using UniProt Q43077 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Primary amine oxidase |
| Target Type | SINGLE PROTEIN |
| Organism | Pisum sativum |
| UniProt | Q43077 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Primary amine oxidase |
| UniProt Accession | Q43077 |
| Component Type | Protein |
| Sequence Length | 674 aa |
Primary amine oxidase
How to read this target
Review this target as Primary amine oxidase, mapped to UniProt Q43077. Sequence length is 674 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL534914 | 6.15 | IC50 | 710.0 | Preclinical |
| CHEMBL537624 | 5.03 | IC50 | 9300.0 | Preclinical |
| CHEMBL534467 | 4.77 | IC50 | 17000.0 | Preclinical |
| CHEMBL537623 | 4.26 | IC50 | 55000.0 | Preclinical |
| CHEMBL541126 | 4.05 | IC50 | 89000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 3 assays, 7 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 7 | 4.8 |