Histone deacetylase · SINGLE PROTEIN · Plasmodium falciparum
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt Q9XYC7. Use UniProt Q9XYC7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9XYC7 as the stable identity anchor, then attach disease evidence before program review.
Histone deacetylase
Review this target as Histone deacetylase, mapped to UniProt Q9XYC7. Sequence length is 449 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone deacetylase as ChEMBL target CHEMBL5541, mapped to UniProt Q9XYC7. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Histone deacetylase is the right protein anchor across sources, using UniProt Q9XYC7 as the stable mapping.
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| Preferred Name | Histone deacetylase |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
| UniProt | Q9XYC7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone deacetylase |
| UniProt Accession | Q9XYC7 |
| Component Type | Protein |
| Sequence Length | 449 aa |
Histone deacetylase
Review this target as Histone deacetylase, mapped to UniProt Q9XYC7. Sequence length is 449 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL99 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL343448 | 9.05 | IC50 | 0.9 | Approved |
| CHEMBL430060 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL483254 | 8.74 | IC50 | 1.8 | Approved |
| CHEMBL1214760 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL490032 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL519035 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL490229 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL506834 | 7.54 | IC50 | 29.0 | Preclinical |
| CHEMBL307765 | 7.44 | IC50 | 36.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 11 | 7.4 |
| cell-based format | 2 | 22 | 7.5 |