Atypical kinase COQ8A, mitochondrial · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8NI60. Use UniProt Q8NI60 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8NI60 as the stable identity anchor, then attach disease evidence before program review.
Atypical kinase COQ8A, mitochondrial
Review this target as Atypical kinase COQ8A, mitochondrial, mapped to UniProt Q8NI60. Sequence length is 647 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Atypical kinase COQ8A, mitochondrial as ChEMBL target CHEMBL5550, mapped to UniProt Q8NI60. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Atypical kinase COQ8A, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8NI60 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Atypical kinase COQ8A, mitochondrial |
| UniProt Accession | Q8NI60 |
| Component Type | Protein |
| Sequence Length | 647 aa |
Atypical kinase COQ8A, mitochondrial
Review this target as Atypical kinase COQ8A, mitochondrial, mapped to UniProt Q8NI60. Sequence length is 647 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4575895 | 7.18 | Kd | 66.0 | Preclinical |
| CHEMBL230011 | 7.03 | Kd | 94.0 | Clinical |
| CHEMBL4556662 | 6.77 | Kd | 170.0 | Preclinical |
| CHEMBL4585158 | 6.77 | Kd | 170.0 | Preclinical |
| CHEMBL4443342 | 6.72 | Kd | 190.0 | Preclinical |
| CHEMBL4517424 | 6.72 | Kd | 190.0 | Preclinical |
| CHEMBL5416410 | 6.72 | Kd | 190.0 | Approved |
| CHEMBL535429 | 6.66 | Kd | 220.0 | Preclinical |
| CHEMBL311959 | 6.6 | Kd | 250.0 | Preclinical |
| CHEMBL217092 | 6.56 | Kd | 275.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 61 | 16 | 6.0 |
| assay format | 27 | 11 | 6.5 |
| cell-based format | 4 | 0 | — |
| subcellular format | 1 | 6 | 5.5 |