Luciferin 4-monooxygenase · SINGLE PROTEIN · Photinus pyralis
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As of 2026-09-13Protein identity stays anchored to UniProt P08659. Use UniProt P08659 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08659 as the stable identity anchor, then attach disease evidence before program review.
Luciferin 4-monooxygenase
Review this target as Luciferin 4-monooxygenase, mapped to UniProt P08659. Sequence length is 550 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Luciferin 4-monooxygenase as ChEMBL target CHEMBL5567, mapped to UniProt P08659. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Luciferin 4-monooxygenase |
| Target Type | SINGLE PROTEIN |
| Organism | Photinus pyralis |
| UniProt | P08659 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Luciferin 4-monooxygenase |
| UniProt Accession | P08659 |
| Component Type | Protein |
| Sequence Length | 550 aa |
Luciferin 4-monooxygenase
Review this target as Luciferin 4-monooxygenase, mapped to UniProt P08659. Sequence length is 550 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2324047 | 9.59 | IC50 | 0.257 | Preclinical |
| CHEMBL2324088 | 9.54 | IC50 | 0.2884 | Preclinical |
| CHEMBL2324042 | 9.51 | IC50 | 0.309 | Preclinical |
| CHEMBL2324086 | 9.4 | IC50 | 0.3981 | Preclinical |
| CHEMBL2324045 | 9.28 | IC50 | 0.5248 | Preclinical |
| CHEMBL2324053 | 9.13 | IC50 | 0.7413 | Preclinical |
| CHEMBL2324097 | 9.08 | IC50 | 0.8318 | Preclinical |
| CHEMBL2324068 | 9.06 | IC50 | 0.871 | Preclinical |
| CHEMBL2324051 | 9.05 | IC50 | 0.8913 | Preclinical |
| CHEMBL2324082 | 9.04 | IC50 | 0.912 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 26 | 523 | 5.8 |
| cell-based format | 19 | 2 | 6.5 |
| assay format | 17 | 64 | 5.9 |
| biochemical format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 13 | 0 | — |
| cell-based format | 3 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |