Skip to main content
Free research Free research Free target review with research home and workspace preview
Quick search ChEMBL 36
Loading Target Snapshot...
Querying ChEMBL database. This may take a few seconds.
Target Snapshot

CHEMBL5595 Target Snapshot

Gastrin/cholecystokinin type B receptor · SINGLE PROTEIN · Canis lupus familiaris

19Compounds
12Assays
0Approved Drugs
20.0Activities
Free Research Context

Research home keeps recent targets

This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.

Navigation

Switch target

Move to another high-traffic target or paste a specific ChEMBL target ID.

Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P30552. Use UniProt P30552 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P30552 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Gastrin/cholecystokinin type B receptor as ChEMBL target CHEMBL5595, mapped to UniProt P30552. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Gastrin/cholecystokinin type B receptor
SINGLE PROTEIN · Canis lupus familiaris
As of 2026-09-14
ChEMBL target ID
CHEMBL5595
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P30552
Gastrin/cholecystokinin type B receptor
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Gastrin/cholecystokinin type B receptor is the right protein anchor across sources, using UniProt P30552 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelGastrin/cholecystokinin type B receptor
UniProt AccessionP30552
Component TypeProtein
Sequence Length453 aa

Gastrin/cholecystokinin type B receptor

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Gastrin/cholecystokinin type B receptor, mapped to UniProt P30552. Sequence length is 453 aa.

Mapped IDP30552
Review nameGastrin/cholecystokinin type B receptor
OrganismCanis lupus familiaris
Assay Mix

Activity Type Distribution

IC505.0
KI15.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL389711 8.62 Ki 2.399 Preclinical
CHEMBL226533 8.5 Ki 3.162 Preclinical
CHEMBL227330 8.37 Ki 4.266 Preclinical
CHEMBL226583 8.35 Ki 4.467 Preclinical
CHEMBL227276 8.35 Ki 4.467 Preclinical
CHEMBL227254 8.33 Ki 4.677 Preclinical
CHEMBL227333 8.32 Ki 4.786 Preclinical
CHEMBL226673 8.28 Ki 5.248 Preclinical
CHEMBL389639 8.24 Ki 5.754 Preclinical
CHEMBL387948 8.2 Ki 6.31 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
2
7.0
7
7.5
9
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

12
Total Assays
14
Tested Compounds
2
Assay Types
Binding — 6 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 6 6 7.6
Functional — 6 assays, 14 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 5 0
tissue-based format 1 14 8.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine