TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q15750. Use UniProt Q15750 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q15750 as the stable identity anchor, then attach disease evidence before program review.
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Review this target as TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, mapped to UniProt Q15750. Sequence length is 504 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 as ChEMBL target CHEMBL5605, mapped to UniProt Q15750. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q15750 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 |
| UniProt Accession | Q15750 |
| Component Type | Protein |
| Sequence Length | 504 aa |
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Review this target as TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, mapped to UniProt Q15750. Sequence length is 504 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3953067 | 8.51 | IC50 | 3.1 | Preclinical |
| CHEMBL3916326 | 8.37 | IC50 | 4.3 | Preclinical |
| CHEMBL3924740 | 8.36 | IC50 | 4.4 | Preclinical |
| CHEMBL3919781 | 8.28 | IC50 | 5.2 | Preclinical |
| CHEMBL3917140 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL3898170 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL3912681 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL3905384 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL3901893 | 7.48 | IC50 | 33.0 | Preclinical |
| CHEMBL388978 | 7.46 | IC50 | 35.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 11 | 38 | 6.9 |
| cell-based format | 2 | 0 | — |