Proteasome subunit beta type-8 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P28062. Use UniProt P28062 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P28062 as the stable identity anchor, then attach disease evidence before program review.
Proteasome subunit beta type-8
Review this target as Proteasome subunit beta type-8, mapped to UniProt P28062. Sequence length is 276 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Proteasome subunit beta type-8 as ChEMBL target CHEMBL5620, mapped to UniProt P28062. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Proteasome subunit beta type-8 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P28062 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proteasome subunit beta type-8 |
| UniProt Accession | P28062 |
| Component Type | Protein |
| Sequence Length | 276 aa |
Proteasome subunit beta type-8
Review this target as Proteasome subunit beta type-8, mapped to UniProt P28062. Sequence length is 276 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4751044 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4784875 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL4741140 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL5175132 | 9.03 | IC50 | 0.94 | Preclinical |
| CHEMBL5180795 | 8.97 | IC50 | 1.07 | Preclinical |
| CHEMBL3218837 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL5201806 | 8.93 | IC50 | 1.17 | Preclinical |
| CHEMBL3319587 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL4796570 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL325041 | 8.89 | IC50 | 1.3 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 59 | 366 | 6.6 |
| cell-based format | 24 | 83 | 7.2 |
| subcellular format | 4 | 10 | 5.6 |
| assay format | 2 | 5 | 5.8 |
| tissue-based format | 2 | 34 | 6.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 35 | 6.2 |